Research Interest:

Valorization of agri-biomass through the formation of functional materials (nanomaterials, coatings, hydrogels, films etc) for agricultural and biomedical applications.

Educational Background:

• 2002-2007, Ph.D. in Organic and Bioorganic Chemistry, North Carolina State University, Raleigh, USA
• 2006, M.S. in Organic Chemistry, North Carolina State University, Raleigh, USA
• 1999-2001, M.Sc. in Physical Chemistry, Kalyani University, West Bengal, India
• 1996-1999, B.Sc. in Chemistry (Hons.), University of Calcutta, West Bengal, India

Positions held:

• 2022-till date Scientist-E (Nanomaterials and Application Technology), Center of Innovative and Applied Bioprocessing (CIAB), Department of Biotechnology, Government of India, Mohali, Punjab
• 2016-2021, Scientist-D (Nanomaterials and Application Technology), Center of Innovative and Applied Bioprocessing (CIAB), Department of Biotechnology, Government of India, Mohali, Punjab
• 5/2018-till date, Adjunct Assistant Professor, Regional Centre for Biotechnology (RCB), Govt. of India
• 2016, Assistant Professor, National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, West Bengal
• 2012-2015, DST-WOSA Scientist, National Institute of Pharmaceutical Education and Research (NIPER), Mohali, Punjab
• 1/2012- 12/2013, Visiting Scientist, Harvard Medical School, Boston, MA, USA
• 2010–2011, US NIH Postdoctoral Fellow, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
• 2007–2010, US NIH Postdoctoral Fellow, Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
• 2002–2007, Research and Teaching Assistant, North Carolina State University, Raleigh, NC, USA.

Selected Publications :

•Reddy, Y. N.#,; De, A;# Paul, S.; Pujari, A; Bhaumik, J.* In-situ Nanoarchitectonics of MOF Hydrogel: A Self-Adhesive and pH-Responsive Smart Platform for Phototherapeutic Delivery. Biomacromolccules 2023, 24, 4, 1717–1730 (#Equal contribution)
•Reddy, Y. N., Kirar, S.#; Thakur, N. S.#; Patil, M. D.; Bhaumik, J.* “Sunlight Assisted Photocatalytic Degradation of Lignin using Recyclable Light Harvesters.” ACS Sus. Chem. Eng, 2023, 11, 12, 4568–4579 DOI: 10.1021/acssuschemeng.2c05917, (#Equal contribution)
• Chandna, S.; Paul, S.; Kaur, R.; Gogde, K.; Bhaumik, J. Photodynamic Lignin Hydrogels: A Versatile Self-Healing Platform for Sustained Release of Photosensitizer Nanoconjugates. ACS Applied Polymer Materials, 2022 DOI: 10.1021/acsapm.2c01319.
• Kirar, S.; Reddy Y. N.; Banerjee, U. C., Bhaumik, J. Development of Heterocyclic BODIPY-based Polymeric Nanoparticles for Pathogen Inhibition using Photodynamic Therapy. ChemPhotoChem, 2022, DOI:10.1002/cptc.202200172.
• De, A.; Paul, S.; Reddy, Y. N.; Sharma, V.; Bhaumik, J.; Tippavajhala, V. K.* Lung-on-chip: Its current and future perspective on pharmaceutical and biomedical applications, Journal of Drug Delivery Science and Technology, 2022, 103930.
• Paul S, Thakur NS, Chandna S, Sagar V, Bhaumik J (2022) Lignin-Based CdS Dots as multifunctional platform for sensing and wearable photodynamic coatings. ACS Applied Nano Materials. 2022, 5, 2, 2748–2761, DOI: 10.1021/acsanm.1c04427.
• Kaur, R.; Thakur, N. S.; Chandna, S.; Bhaumik, J.* Sustainable Lignin-Based Coatings Doped with Titanium Dioxide Nanocomposites Exhibit Synergistic Microbicidal and UV Blocking Performance Towards Personal Protective Equipment, ACS Sus. Chem. Eng, 2021, 9, 11223–11237.
• Kaur, R.; Bhardwaj, S. K.; Chandna, S. Kim, K. H. Bhaumik, J.* Lignin-based Metal Oxide Nanocomposites for UV Protection Applications: A Review, Journal of Cleaner Production 2021, 317, 128300.
• Kirar, S.; Chaudhari, D.; Thakur, N. S.; Jain, S.; Bhaumik, J.; Laha, J. K.; Banerjee, U. C. Light-assisted anticancer photodynamic therapy using porphyrin-doped nanoencapsulates, Journal of Photochemistry and Photobiology B: Biology, 2021, 220, 112209.
• Thakur, N. S.; Mandal, N.; Patel, G.; Kirar, S.; Reddy Y. N., Kushwah, V.; Jain, S.; Kalia, Y. N.; Bhaumik, J.*; Banerjee, U. C. Co-administration of zinc phthalocyanine and quercetin via hybrid nanoparticles for augmented photodynamic therapy, Nanomedicine: Nanotechnology, Biology and Medicine, 2021, 33, 102368.
• Bhardwaj, S. K.; Singh, H.; Deep, A.; Khatri, M.; Bhaumik, J. Kim, K.-H.; Bhardwaj, N UVC-Based Photoinactivation as an Efficient Tool to Control the Transmission of Coronaviruses, Science of The Total Environment 2021, 792, 148548.
• Kirar, S.; Thakur, N. S.; Reddy Y. N., Banerjee, U. C., Bhaumik, J.* Insights on the polypyrrole based nanoformulations for photodynamic therapy, Journal of Porphyrins and Phthalocyanines, 2021, doi.org/10.1142/S1088424621300032.
• Hunjan, M. K.; Panday, S.; Gupta, A.; Bhaumik, J.; Das, P. Laha, J. K. Recent advances in functionalization of pyrroles and their translational potential, The Chemical Record, 2021, 21, 715-780
• Bhardwaj, S. K.; Bhardwaj, N.; Kumar, V. Bhatt, D.; Azzouz, A.; Bhaumik, J.; Kim, K.-H.; Deep, A. Recent progress in nanomaterial-based sensing of airborne viral and bacterial pathogens, Environment International, 2021, 146, 106183.
• Paul S, Thakur NS, Chandna S, Reddy YN, Bhaumik J* (2021) Development of a light activatable lignin nanosphere based spray coating for bioimaging and antimicrobial photodynamic therapy, Journal of Materials Chemistry B, DOI: 10.1039/D0TB02643C
• Chandna S, Thakur, N S, Kaur R, Bhaumik J.* Lignin-Bimetallic Nanoconjugate Doped pH-Responsive Hydrogels for Laser-Assisted Antimicrobial Photodynamic Therapy. Biomacromolecules 2020, DOI: 10.1021/acs.biomac.0c00695
• Kaur, R.; Thakur, N. S.; Chandna, S.; Bhaumik, J.* “Development of Agri-Biomass Based Lignin Derived Zinc Oxide Nanocomposites as Promising UV Protectant-cum-Antimicrobial Agents, J. Mater. Chem. B, 2020, 8, 260-269. DOI: 10.1039/C9TB01569H.
• Reddy, Y. N.; Thakur, N. S.; Bhaumik, J.* “Harnessing the Photocatalytic Potential of Polypyrroles in Water through Nanointervension: Synthesis and Photophysical Evaluation of Biodegradable Polypyrrolic Nanoencapsulates”, ChemNanoMat 2019, DOI: 10.1002/cnma.201900466.
• Chandna, S.; Thakur, N. S.; Reddy, Y. N.; Kaur, R.; Bhaumik, J.* “Engineering Lignin Stabilized Bimetallic Nanocomplexes: Structure, Mechanistic Elucidation, Antioxidant and Antimicrobial Potential”, ACS Biomat. Sc. Engg. 2019, 5, 3212-3227.
• Kirar, S.; Thakur, N. S. Laha, J. K.; Bhaumik, J.; Banerjee, U. C. “Development of Gelatin Nanoparticle-Based Biodegradable Phototheranostic Agents: Advanced System to Treat Infectious Diseases”, ACS Biomat. Sc. Engg. 2018, 4, 473–482.
• Thakur, N. S.; Bhaumik, J;* Kirar, S; and Banerjee, U. C.* ‘’Development of gold-based phototheranostic nanoagents through bioinspired route and their applications in photodynamic therapy’’, ACS Sus. Chem. Eng, 2017, 5, 7950-7960.
• Dwivedee, B. P.; Bhaumik, J.*; Rai, S. K.; Laha, J. K. Banerjee, U. C. “Development of nanobiocatalysts employing statistical design as an optimization tool for efficient immobilization of biocatalysts”, Bioresource Technology 2017, 239, 464-471.
• Bhaumik, J.;* Gogia, G.; Kirar, S.; Vijay, L. Thakur, N. S.; Banerjee, U. C.; Laha, J. K.* “Bioinspired nanophotosensitizers: synthesis and characterization of porphyrin–noble metal nanoparticle conjugates”, New J. Chem. 2016, 40, 724-731.
• Patil M. D., Bhaumik, J.; Babykutty, S. Fukumura, D.; Banerjee, U. C. “Arginine Dependence of Tumor Cells: Targeting a Chink in Cancer's Armor”, Oncogene (Nature Publishing Group) 2016, 35, 4957-4972.
• Bhaumik J.;* Thakur, N. S.; Aili, P. K.; Ghanghoriya, A.; Mittal, A. K.; Banerjee, U. C.* “Bioinspired Nanotheranostic Agents: Synthesis, Surface Functionalization and Antioxidant Potential”, ACS Biomat. Sc. and Engg. 2015, 1, 382-392.
• Bhaumik, J.;* Mittal, A. K.; Banerjee, A.; Chisti, Y.; Banerjee, U. C.* “Applications of Phototheranostic Nanoagents in Photodynamic Therapy”, Nano Research 2015, 8, 1373-1394.
• Han, H.-S.; Niemeyer, E.; Huang, Y.; Kamoun, W. S.; Martin, J. D.; Bhaumik, J.; Chen, Y.; Roberge, S.; Cui, J.; Martin, M. R.; Fukumura, D.; Jain, R. K.; Bawendi, M. G.; Duda, D. G. “Quantum Dot/Antibody Conjugates for In vivo Cytometric Imaging in Mice”, Proc. Natl. Acad. Sci. USA 2015, 112, 1350-1355.
• Dwivedee, B. P.; Ghosh, S.; Bhaumik, J.; Banoth, L.; Banerjee, U. C. “Lipase Catalyzed Green Synthesis of Enantiopure Atenolol”, RSC Adv. 2015, 5, 15850-15860.
• McCarthy, J. R.*; Bhaumik, J.; Karver, M. R.; Erdem, S. S.; Weissleder, R. “Targeted Nanoagents for the Detection of Cancers”, Mol. Oncol. 2010, 4, 511-528.
• Bhaumik, J.; McCarthy, J. R.; Weissleder, R. “Synthesis and Photophysical Properties of Sulfonamidophenyl Porphyrins as Models for Activatable Photosensitizers”, J. Org. Chem. 2009, 74, 5894-5901.
• Bhaumik, J.#; McCarthy, J. R.#; Merbouh, N.; Weissleder, R. “High-yielding Syntheses of Hydrophilic, Conjugatable Chlorins and Bacteriochlorins”, Org. Biomol. Chem. 2009, 7, 3430-3436. # Equal contribution (first author)
• Mroz, P.; Bhaumik, J.; Dogutan, D. K.; Aly, Z.; Kamal, Z.; Khalid, L.; Kee, H. L.; Bocian, D. F.; Holten, D.; Lindsey, J. S.; Hamblin, M. R. “Imidazole Metalloporphyrins as Photosensitizers for Photodynamic Therapy: Role of Molecular Charge, Central Metal and Hydroxyl Radical Production”, Cancer Lett. 2009, 282, 63-76.
• Muthiah, C.; Bhaumik, J.; Lindsey, J. S. “Rational Routes to Formyl-Substituted Chlorins”, J. Org. Chem. 2007, 72, 5839-5842.
• Bhaumik, J.; Yao, Z.; Borbas, K. E.; Taniguchi, M.; Lindsey, J. S. “Masked Imidazolyl-Dipyrromethanes in the Synthesis of Imidazole-Substituted Porphyrins”, J. Org. Chem. 2006, 71, 8807-8817.

Patents:

• Facile, green and high yielding process to synthesize lignin nanocarriers and evaluation of their functional properties thereof. Indian Patent Appl. 201911011852. Patent No. 445568. Inventors: Bhaumik J, Thakur NS, Paul S.
• Process for the production of nanofilms through agro-biomass derived lignin and applications thereof, Indian patent application no: 202211070754. Inventors: Bhaumik J, Goswami S, Kirar S, Singh M, Mohne D.
• A Biocatalytic Process for the Production of ω-Amino Fatty Acids, Precursors of Nylon Bioplastics, Indian patent application no: 202211067282. Inventors: Patil MD, Bhaumik J, Meenal
• Synthesis of lignin based bio-nano-fertilizers and bio-nano-pesticides and applications thereof, Indian patent application no: 202211066111. Inventors: Bhaumik J, Kaur R., De A., Paul S., Pujari AK, Gogde K.
• J. Bhaumik, Y. N. Reddy, N. S. Thakur and S. Chandna, “Simple and one-pot processes to develop polypyrrolic compounds in scalable manner and development of their nano formulations through encapsulation or conjugation forming photosynthetic nanopigments for light harvesting applications thereof”; Indian patent application no: 201811044076, filed on 22nd November, 2018. (Patent granted, no. 374672)
• Lignin based polypyrrole nanoformulations as highly effective antiviral agents against SARS-CoV-2. Indian patent application no: 202111014735, Inventors: Bhaumik J, Vrati S, Reddy YN, Chandna S, Paul S, Kaur R, Agarwal S and Chandru S. (Joint applicants: DBT-CIAB and DBT-RCB)
• One pot, greener synthesis of agri-biomass lignin derived fluorescent metal nanoclusters and applications thereof.Indian patent Appl No: 202011028996 . Inventors: Bhaumik J, Thakur NS, Paul S, Reddy YN
• Light activatable polypyrrolic metal organic framework composites and applications thereof. Indian patent Appl No: 202011028994. Inventors: Bhaumik J, Bhardwaj SK, Reddy YN, Kaur R
• J. Bhaumik, N. S. Thakur and S. Paul. “A Facile, Green and High Yielding Process to Synthesize Lignin Nanocarriers and Evaluation of Their Functional Properties Thereof.” Indian patent application no: 201911011852
• J. Bhaumik, R. Kaur, S. Chandna, Y. N. Reddy and N. S. Thakur. “Agri-biomass derived lignin based green metal oxide nanocomposites for UV protective, antimicrobial and photocatalytic applications”, Indian patent application no: 201811048498
• J. Bhaumik, S. Chandna, R. S. Sangwan, “An improvised, sustainable and economical process for the synthesis of biomass derived lignin coated metal nanocomplexes and development of nanotherapeutic and nanodiagnostic conjugates thereof”; Indian patent application no: R20171038321, filed on 29th December, 2017.)

List of Book Chapters:

•Sharma, A., Paul, S., Charu, Kaur, R., Bhaumik, J.* and Pal, S.*, Lignin-based hybrid materials in wastewater cleanup, in Metagenomics to Bioremediations, published by Elsevier, 2022.
•Kaur, R.; Chandna, S.; Bhardwaj, S. K.; Bhaumik, J.* Development of Lignin-based Metal Oxide Nanocomposites for their Applications in Photocatalysis, book chapter, book title: Sustainable Agriculture Reviews 56; Bioconversion of Food and Agricultural Waste into Value-added Materials’’ Editors: A. Rana, A. Saneja, S. Kumar and E. Lichtfouse, published by Springer Nature, 2022.
•Chandna, S., Gogde, K., Kaur, R., Sagar, V. and Bhaumik, J.* “Nano-Biosensors for Plant Biomass: Concept and Applications”. In Role of nanoparticles in plant nutrition under soil pollution, Springer. 2022. 199-222.
•Reddy, Y. N.; Gogde, K.; Paul, S. Bhaumik, J.* Lignin to Platform Chemicals and Biomaterials, book chapter, book title: Biomass for Bioenergy and Biomaterials; Editors: Adlakha, N.; Bhatnagar, R.; Yazdani; S. S.; publisher: CRC Press, 2021, 34.
•Chandna, S.; Bhardwaj, S. K.; Paul, S.; Bhaumik, J.* Synthesis, and Applications of Lignin-Derived Hydrogels, In: Sharma S., Kumar A. (eds) Lignin. Springer Series on Polymer and Composite Materials. Springer, Cham, 2020, 231-252.
•Paul, S.; Bhardwaj, S. K.; Kaur, R.; Bhaumik, J.* ‘Lignin-Derived Hybrid Materials as Promising Adsorbents for the Separation of Pollutants’, Chapter 8, 225-261, Editors: Chernyshova et al.; Multidisciplinary Advances in Efficient Separation Processes, ACS Symposium Series; American Chemical Society: Washington, DC, 2020.
• Bhaumik, J.;* Kirar, S.; Laha, J. K. “Theranostic nanoconjugates of tetrapyrrolic macrocycles and their applications in photodynamic therapy”, Book chapter no 22, , Publisher: Springer, Book Title: Redox-Active Therapeutics, 2016, 509-524.
• Thakur, N. S.; Dwivedee, B. P.; Banerjee, U. C.; Bhaumik, J.* “Bioinspired Synthesis of Silver Nanoparticles: Characterization, Mechanism and Applications”, book chapter, Book title: ‘Silver Nanoparticles for Antibacterial Devices’; publisher: CRC Press/Taylor and Francis Group 2017, 3-36.

Fellowships/Awards/Honors (Selected):

1. Member of the Royal Society of Chemistry (RSC), since 2022
2. Life Member, Chemical Research Society of India (CRSI), since 2022
3. Department of Science and Technology (DST), Govt. of India ‘International Travel Award’ to attend an international conference [256th American Chemical Society (ACS) National Meeting] held in Boston, USA from August 19-23, 2018
4. Member of the American Chemical Society (ACS), 2006-till date.
5. Life Member, The Biotech Research Society of India (BRSI), 2016-till date.
6.‘Recognized Reviewer Status’ awarded by Elsevier, August 2016.
7.‘Chemistry Ambassador’ appointed by American Chemical Society (ACS) since 2015.
8. Research article on bioinspired noble metal nanoparticles has been selected to be featured on the cover of the sixth issue of ACS Biomaterial Science and Engineering journal, June 2015.
9. Research work highlighted as ‘Highly rated paper’ (top 2% among ~7000 abstracts) at the 102nd Annual American Association for Cancer Research (AACR) Meeting, Florida, USA, April 2-6, 2011.
10. Awarded NIH postdoctoral fellowship to carry out research at Harvard Medical School, USA 2007-2011.
11. Awarded ‘Graduate Research Scholarship’ to attend PhD program in North Carolina State University, USA, 2002-2007.